| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10013889 | HBV | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS30082490 | HIV | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS20009984 | HPV | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS20068354 | HPV | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS20016744 | HPV | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS44018189 | HTLV-1 | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS44033835 | HTLV-1 | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CD22 |
|---|---|
| DrugBank ID | DB12688 |
| Drug Name | Moxetumomab pasudotox |
| Target ID | BE0000183 |
| UniProt ID | P20273 |
| Regulation Type | binder |
| PubMed IDs | 22355051; 22003067; 33807678 |
| Citations | Park JH, Levine RL: Targeted immunotherapy for hairy cell leukemia. J Clin Oncol. 2012 May 20;30(15):1888-90. doi: 10.1200/JCO.2011.39.8313. Epub 2012 Feb 21.@@Kreitman RJ, Pastan I: Antibody fusion proteins: anti-CD22 recombinant immunotoxin moxetumomab pasudotox. Clin Cancer Res. 2011 Oct 15;17(20):6398-405. doi: 10.1158/1078-0432.CCR-11-0487.@@Kyriakidis I, Vasileiou E, Rossig C, Roilides E, Groll AH, Tragiannidis A: Invasive Fungal Diseases in Children with Hematological Malignancies Treated with Therapies That Target Cell Surface Antigens: Monoclonal Antibodies, Immune Checkpoint Inhibitors and CAR T-Cell Therapies. J Fungi (Basel). 2021 Mar 5;7(3). pii: jof7030186. doi: 10.3390/jof7030186. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |
