| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10013889 | HBV | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS30082490 | HIV | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS20009984 | HPV | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS20068354 | HPV | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS20016744 | HPV | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS44018189 | HTLV-1 | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
| TVIS44033835 | HTLV-1 | ENSG00000012124.17 | protein_coding | CD22 | No | No | 933 | P20273 Q0EAF5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CD22 |
|---|---|
| DrugBank ID | DB04958 |
| Drug Name | Epratuzumab |
| Target ID | BE0000183 |
| UniProt ID | P20273 |
| Regulation Type | antibody |
| PubMed IDs | 16918261; 17530024; 16814387; 33807678 |
| Citations | Steinfeld SD, Youinou P: Epratuzumab (humanised anti-CD22 antibody) in autoimmune diseases. Expert Opin Biol Ther. 2006 Sep;6(9):943-9.@@Leonard JP, Goldenberg DM: Preclinical and clinical evaluation of epratuzumab (anti-CD22 IgG) in B-cell malignancies. Oncogene. 2007 May 28;26(25):3704-13.@@Carnahan J, Stein R, Qu Z, Hess K, Cesano A, Hansen HJ, Goldenberg DM: Epratuzumab, a CD22-targeting recombinant humanized antibody with a different mode of action from rituximab. Mol Immunol. 2007 Feb;44(6):1331-41. Epub 2006 Jun 30.@@Kyriakidis I, Vasileiou E, Rossig C, Roilides E, Groll AH, Tragiannidis A: Invasive Fungal Diseases in Children with Hematological Malignancies Treated with Therapies That Target Cell Surface Antigens: Monoclonal Antibodies, Immune Checkpoint Inhibitors and CAR T-Cell Therapies. J Fungi (Basel). 2021 Mar 5;7(3). pii: jof7030186. doi: 10.3390/jof7030186. |
| Groups | Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |
