| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017649 | HBV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS30030581 | HIV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS30030582 | HIV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS30030583 | HIV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS20037299 | HPV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS20014150 | HPV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS20032478 | HPV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS44017386 | HTLV-1 | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS44046649 | HTLV-1 | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CPT1A |
|---|---|
| DrugBank ID | DB01074 |
| Drug Name | Perhexiline |
| Target ID | BE0000406 |
| UniProt ID | P50416 |
| Regulation Type | inhibitor |
| PubMed IDs | 17139284; 17016423; 11117381; 16306812; 8694852; 17445089; 11752352 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Kennedy JA, Kiosoglous AJ, Murphy GA, Pelle MA, Horowitz JD: Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart. J Cardiovasc Pharmacol. 2000 Dec;36(6):794-801.@@Unger SA, Kennedy JA, McFadden-Lewis K, Minerds K, Murphy GA, Horowitz JD: Dissociation between metabolic and efficiency effects of perhexiline in normoxic rat myocardium. J Cardiovasc Pharmacol. 2005 Dec;46(6):849-55.@@Kennedy JA, Unger SA, Horowitz JD: Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone. Biochem Pharmacol. 1996 Jul 26;52(2):273-80.@@Ashrafian H, Horowitz JD, Frenneaux MP: Perhexiline. Cardiovasc Drug Rev. 2007 Spring;25(1):76-97.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | Piperidines |
| SMILES | C(C(C1CCCCC1)C1CCCCC1)C1CCCCN1 |
| Pathways | |
| PharmGKB | PA130150436 |
| ChEMBL | CHEMBL75880 |
