| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017649 | HBV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS30030581 | HIV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS30030582 | HIV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS30030583 | HIV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS20037299 | HPV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS20014150 | HPV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS20032478 | HPV | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS44017386 | HTLV-1 | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
| TVIS44046649 | HTLV-1 | ENSG00000110090.13 | protein_coding | CPT1A | No | No | 1374 | P50416 Q8WZ48 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CPT1A |
|---|---|
| DrugBank ID | DB00583 |
| Drug Name | Levocarnitine |
| Target ID | BE0000406 |
| UniProt ID | P50416 |
| Regulation Type | activator |
| PubMed IDs | 12705401; 14711372; 15647998; 16283381; 16362726; 11752352 |
| Citations | Xu ZR, Wang MQ, Mao HX, Zhan XA, Hu CH: Effects of L-carnitine on growth performance, carcass composition, and metabolism of lipids in male broilers. Poult Sci. 2003 Mar;82(3):408-13.@@Morillas M, Lopez-Vinas E, Valencia A, Serra D, Gomez-Puertas P, Hegardt FG, Asins G: Structural model of carnitine palmitoyltransferase I based on the carnitine acetyltransferase crystal. Biochem J. 2004 May 1;379(Pt 3):777-84.@@Tripodi G, Modica R, Stella A, Bigatti G, Bianchi G, Stella P: Haplotype analysis of carnitine transporters and left ventricular mass in human essential hypertension. J Ren Nutr. 2005 Jan;15(1):2-7.@@Waldner R, Laschan C, Lohninger A, Gessner M, Tuchler H, Huemer M, Spiegel W, Karlic H: Effects of doxorubicin-containing chemotherapy and a combination with L-carnitine on oxidative metabolism in patients with non-Hodgkin lymphoma. J Cancer Res Clin Oncol. 2006 Feb;132(2):121-8. Epub 2005 Nov 8.@@Shin ES, Cho SY, Lee EH, Lee SJ, Chang IS, Lee TR: Positive regulation of hepatic carnitine palmitoyl transferase 1A (CPT1A) activities by soy isoflavones and L-carnitine. Eur J Nutr. 2006 Mar;45(3):159-64. Epub 2005 Dec 20.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | Carnitines |
| SMILES | C[N+](C)(C)C[C@H](O)CC([O-])=O |
| Pathways | Carnitine Palmitoyl Transferase Deficiency II; Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD); Ethylmalonic Encephalopathy; Glutaric Aciduria Type I; Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency); Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD); Carnitine Palmitoyl Transferase Deficiency I; Oxidation of Branched-Chain Fatty Acids; Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids; Fatty Acid Metabolism; Beta Oxidation of Very Long Chain Fatty Acids; Carnitine-Acylcarnitine Translocase Deficiency; Carnitine Synthesis; Trifunctional Protein Deficiency; Adrenoleukodystrophy, X-Linked; Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD) |
| PharmGKB | PA450154 |
| ChEMBL | CHEMBL1149 |
