| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10044928 | HBV | ENSG00000173198.6 | protein_coding | CYSLTR1 | No | No | 10800 | Q9Y271 |
| TVIS44029725 | HTLV-1 | ENSG00000173198.6 | protein_coding | CYSLTR1 | No | No | 10800 | Q9Y271 |
| TVIS44051802 | HTLV-1 | ENSG00000173198.6 | protein_coding | CYSLTR1 | No | No | 10800 | Q9Y271 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | CYSLTR1 |
|---|---|
| DrugBank ID | DB00587 |
| Drug Name | Cinalukast |
| Target ID | BE0000705 |
| UniProt ID | Q9Y271 |
| Regulation Type | antagonist |
| PubMed IDs | 11752352; 9042047; 19826192; 23859232; 32179525 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Adelroth E, Inman MD, Summers E, Pace D, Modi M, O'Byrne PM: Prolonged protection against exercise-induced bronchoconstriction by the leukotriene D4-receptor antagonist cinalukast. J Allergy Clin Immunol. 1997 Feb;99(2):210-5.@@Foller M, Mahmud H, Gu S, Wang K, Floride E, Kucherenko Y, Luik S, Laufer S, Lang F: Participation of leukotriene C(4) in the regulation of suicidal erythrocyte death. J Physiol Pharmacol. 2009 Sep;60(3):135-43.@@Singh RK, Tandon R, Dastidar SG, Ray A: A review on leukotrienes and their receptors with reference to asthma. J Asthma. 2013 Nov;50(9):922-31. doi: 10.3109/02770903.2013.823447. Epub 2013 Aug 16.@@Ruiz I, Nevers Q, Hernandez E, Ahnou N, Brillet R, Softic L, Donati F, Berry F, Hamadat S, Fourati S, Pawlotsky JM, Ahmed-Belkacem A: MK-571, a Cysteinyl Leukotriene Receptor 1 Antagonist, Inhibits Hepatitis C Virus Replication. Antimicrob Agents Chemother. 2020 May 21;64(6). pii: AAC.02078-19. doi: 10.1128/AAC.02078-19. Print 2020 May 21. |
| Groups | Experimental |
| Direct Classification | Anilides |
| SMILES | CCC(CC)(CC(=O)NC1=CC(C=CC2=NC(=CS2)C2CCC2)=CC=C1)C(O)=O |
| Pathways | |
| PharmGKB | PA164743057 |
| ChEMBL | CHEMBL283754 |
