| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10044928 | HBV | ENSG00000173198.6 | protein_coding | CYSLTR1 | No | No | 10800 | Q9Y271 |
| TVIS44029725 | HTLV-1 | ENSG00000173198.6 | protein_coding | CYSLTR1 | No | No | 10800 | Q9Y271 |
| TVIS44051802 | HTLV-1 | ENSG00000173198.6 | protein_coding | CYSLTR1 | No | No | 10800 | Q9Y271 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CYSLTR1 |
|---|---|
| DrugBank ID | DB11858 |
| Drug Name | Leukotriene D4 |
| Target ID | BE0000705 |
| UniProt ID | Q9Y271 |
| Regulation Type | |
| PubMed IDs | 10391245; 10462554; 12853847 |
| Citations | Lynch KR, O'Neill GP, Liu Q, Im DS, Sawyer N, Metters KM, Coulombe N, Abramovitz M, Figueroa DJ, Zeng Z, Connolly BM, Bai C, Austin CP, Chateauneuf A, Stocco R, Greig GM, Kargman S, Hooks SB, Hosfield E, Williams DL Jr, Ford-Hutchinson AW, Caskey CT, Evans JF: Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature. 1999 Jun 24;399(6738):789-93.@@Sarau HM, Ames RS, Chambers J, Ellis C, Elshourbagy N, Foley JJ, Schmidt DB, Muccitelli RM, Jenkins O, Murdock PR, Herrity NC, Halsey W, Sathe G, Muir AI, Nuthulaganti P, Dytko GM, Buckley PT, Wilson S, Bergsma DJ, Hay DW: Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor. Mol Pharmacol. 1999 Sep;56(3):657-63.@@Bouchelouche K, Andersen L, Nordling J, Horn T, Bouchelouche P: The cysteinyl-leukotriene D4 induces cytosolic Ca2+ elevation and contraction of the human detrusor muscle. J Urol. 2003 Aug;170(2 Pt 1):638-44. |
| Groups | Investigational |
| Direct Classification | Leukotrienes |
| SMILES | CCCCCC=C/CC=C/C=C/C=C/[C@@H](SC[C@H](N)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL288943 |
