| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42000759 | EBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10003545 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10021683 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10030463 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10040017 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10034647 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10043869 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS44008149 | HTLV-1 | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GABRG2 |
|---|---|
| DrugBank ID | DB01205 |
| Drug Name | Flumazenil |
| Target ID | BE0003592 |
| UniProt ID | P18507 |
| Regulation Type | antagonist |
| PubMed IDs | 17974564; 11864636; 8693922 |
| Citations | Padgett CL, Lummis SC: The F-loop of the GABA A receptor gamma2 subunit contributes to benzodiazepine modulation. J Biol Chem. 2008 Feb 1;283(5):2702-8. Epub 2007 Oct 31.@@Wingrove PB, Safo P, Wheat L, Thompson SA, Wafford KA, Whiting PJ: Mechanism of alpha-subunit selectivity of benzodiazepine pharmacology at gamma-aminobutyric acid type A receptors. Eur J Pharmacol. 2002 Feb 15;437(1-2):31-9.@@Whitwam JG, Amrein R: Pharmacology of flumazenil. Acta Anaesthesiol Scand Suppl. 1995;108:3-14. |
| Groups | Approved |
| Direct Classification | Imidazo[1,5-a][1,4]benzodiazepines |
| SMILES | CCOC(=O)C1=C2CN(C)C(=O)C3=C(C=CC(F)=C3)N2C=N1 |
| Pathways | |
| PharmGKB | PA449659 |
| ChEMBL | CHEMBL407 |
