| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42000759 | EBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10003545 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10021683 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10030463 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10040017 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10034647 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS10043869 | HBV | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
| TVIS44008149 | HTLV-1 | ENSG00000113327.17 | protein_coding | GABRG2 | No | No | 2566 | P18507 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GABRG2 |
|---|---|
| DrugBank ID | DB00395 |
| Drug Name | Carisoprodol |
| Target ID | BE0003592 |
| UniProt ID | P18507 |
| Regulation Type | |
| PubMed IDs | 19244096; 20419052; 28642232 |
| Citations | Gonzalez LA, Gatch MB, Taylor CM, Bell-Horner CL, Forster MJ, Dillon GH: Carisoprodol-mediated modulation of GABAA receptors: in vitro and in vivo studies. J Pharmacol Exp Ther. 2009 May;329(2):827-37. doi: 10.1124/jpet.109.151142. Epub 2009 Feb 24.@@Gonzalez LA, Gatch MB, Forster MJ, Dillon GH: Abuse Potential of Soma: the GABA(A) Receptor as a Target. Mol Cell Pharmacol. 2009 Jan 1;1(4):180-186.@@Kumar M, Kumar M, Freund JM, Dillon GH: A Single Amino Acid Residue at Transmembrane Domain 4 of the alpha Subunit Influences Carisoprodol Direct Gating Efficacy at GABAA Receptors. J Pharmacol Exp Ther. 2017 Sep;362(3):395-404. doi: 10.1124/jpet.117.242156. Epub 2017 Jun 22. |
| Groups | Approved |
| Direct Classification | Carbamate esters |
| SMILES | CCCC(C)(COC(N)=O)COC(=O)NC(C)C |
| Pathways | |
| PharmGKB | PA448809 |
| ChEMBL | CHEMBL1233 |
