| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44041843 | HTLV-1 | ENSG00000140443.15 | protein_coding | IGF1R | Yes | No | 3480 | C9J5X1 P08069 |
| TVIS44047281 | HTLV-1 | ENSG00000140443.15 | protein_coding | IGF1R | Yes | No | 3480 | C9J5X1 P08069 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | IGF1R |
|---|---|
| DrugBank ID | DB00047 |
| Drug Name | Insulin glargine |
| Target ID | BE0000858 |
| UniProt ID | P08069 |
| Regulation Type | activator |
| PubMed IDs | 22420005; 20938889; 17922476 |
| Citations | Varewijck AJ, Janssen JA: Insulin and its analogues and their affinities for the IGF1 receptor. Endocr Relat Cancer. 2012 Sep 5;19(5):F63-75. doi: 10.1530/ERC-12-0026. Print 2012 Oct.@@Ciaraldi TP, Sasaoka T: Review on the in vitro interaction of insulin glargine with the insulin/insulin-like growth factor system: potential implications for metabolic and mitogenic activities. Horm Metab Res. 2011 Jan;43(1):1-10. doi: 10.1055/s-0030-1267203. Epub 2010 Oct 11.@@Le Roith D: Insulin glargine and receptor-mediated signalling: clinical implications in treating type 2 diabetes. Diabetes Metab Res Rev. 2007 Nov;23(8):593-9. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA449992 |
| ChEMBL | CHEMBL1201497 |
