Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10001019HBVENSG00000106683.15protein_codingLIMK1NoNo3984P53667
TVIS10024319HBVENSG00000106683.15protein_codingLIMK1NoNo3984P53667
TVIS10030859HBVENSG00000106683.15protein_codingLIMK1NoNo3984P53667
TVIS30088225HIVENSG00000106683.15protein_codingLIMK1NoNo3984P53667
TVIS30067334HIVENSG00000106683.15protein_codingLIMK1NoNo3984P53667
TVIS20065898HPVENSG00000106683.15protein_codingLIMK1NoNo3984P53667
TVIS44035764HTLV-1ENSG00000106683.15protein_codingLIMK1NoNo3984P53667
TCGA Plot Options
Drug Information
GeneLIMK1
DrugBank IDDB12010
Drug NameFostamatinib
Target IDBE0004759
UniProt IDP53667
Regulation Typeinhibitor
PubMed IDs26516587
CitationsRolf MG, Curwen JO, Veldman-Jones M, Eberlein C, Wang J, Harmer A, Hellawell CJ, Braddock M: In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib. Pharmacol Res Perspect. 2015 Oct;3(5):e00175. doi: 10.1002/prp2.175. Epub 2015 Sep 4.
GroupsApproved; Investigational
Direct ClassificationMethoxyanilines
SMILESCOC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC
Pathways
PharmGKB
ChEMBLCHEMBL2103830