| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10012438 | HBV | ENSG00000116711.10 | protein_coding | PLA2G4A | No | No | 5321 | P47712 |
| TVIS10048201 | HBV | ENSG00000116711.10 | protein_coding | PLA2G4A | No | No | 5321 | P47712 |
| TVIS10057697 | HBV | ENSG00000116711.10 | protein_coding | PLA2G4A | No | No | 5321 | P47712 |
| TVIS30081745 | HIV | ENSG00000116711.10 | protein_coding | PLA2G4A | No | No | 5321 | P47712 |
| TVIS30025999 | HIV | ENSG00000116711.10 | protein_coding | PLA2G4A | No | No | 5321 | P47712 |
| TVIS30026000 | HIV | ENSG00000116711.10 | protein_coding | PLA2G4A | No | No | 5321 | P47712 |
| TVIS20000512 | HPV | ENSG00000116711.10 | protein_coding | PLA2G4A | No | No | 5321 | P47712 |
| TVIS20047455 | HPV | ENSG00000116711.10 | protein_coding | PLA2G4A | No | No | 5321 | P47712 |
| TVIS20040280 | HPV | ENSG00000116711.10 | protein_coding | PLA2G4A | No | No | 5321 | P47712 |
| TVIS44033384 | HTLV-1 | ENSG00000116711.10 | protein_coding | PLA2G4A | No | No | 5321 | P47712 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | PLA2G4A |
|---|---|
| DrugBank ID | DB01103 |
| Drug Name | Quinacrine |
| Target ID | BE0000657 |
| UniProt ID | P47712 |
| Regulation Type | inhibitor |
| PubMed IDs | 12110374; 12582837; 9480923 |
| Citations | Hellstrand M, Eriksson E, Nilsson CL: Dopamine D(2) receptor-induced COX-2-mediated production of prostaglandin E(2) in D(2)-transfected Chinese hamster ovary cells without simultaneous administration of a Ca(2+)-mobilizing agent. Biochem Pharmacol. 2002 Jun 15;63(12):2151-8.@@Ong WY, Lu XR, Ong BK, Horrocks LA, Farooqui AA, Lim SK: Quinacrine abolishes increases in cytoplasmic phospholipase A2 mRNA levels in the rat hippocampus after kainate-induced neuronal injury. Exp Brain Res. 2003 Feb;148(4):521-4. Epub 2002 Dec 11.@@Kim BC, Kim JH: Exogenous C2-ceramide activates c-fos serum response element via Rac-dependent signalling pathway. Biochem J. 1998 Mar 1;330 ( Pt 2):1009-14. |
| Groups | Investigational |
| Direct Classification | Acridines |
| SMILES | CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC2=C1C=CC(Cl)=C2 |
| Pathways | |
| PharmGKB | PA164745551 |
| ChEMBL | CHEMBL7568 |
