| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10012333 | HBV | ENSG00000171522.6 | protein_coding | PTGER4 | No | No | 5734 | A0PJF5 P35408 |
| TVIS44000241 | HTLV-1 | ENSG00000171522.6 | protein_coding | PTGER4 | No | No | 5734 | A0PJF5 P35408 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PTGER4 |
|---|---|
| DrugBank ID | DB00929 |
| Drug Name | Misoprostol |
| Target ID | BE0003522 |
| UniProt ID | P35408 |
| Regulation Type | agonist |
| PubMed IDs | 16039053; 18472336; 12097143; 9313928; 11602631; 11993717 |
| Citations | Nakae K, Hayashi F, Hayashi M, Yamamoto N, Iino T, Yoshikawa S, Gupta J: Functional role of prostacyclin receptor in rat dorsal root ganglion neurons. Neurosci Lett. 2005 Nov 18;388(3):132-7.@@Li J, Liang X, Wang Q, Breyer RM, McCullough L, Andreasson K: Misoprostol, an anti-ulcer agent and PGE2 receptor agonist, protects against cerebral ischemia. Neurosci Lett. 2008 Jun 20;438(2):210-5. doi: 10.1016/j.neulet.2008.04.054. Epub 2008 Apr 20.@@Guan Y, Stillman BA, Zhang Y, Schneider A, Saito O, Davis LS, Redha R, Breyer RM, Breyer MD: Cloning and expression of the rabbit prostaglandin EP2 receptor. BMC Pharmacol. 2002 Jun 27;2:14.@@Kiriyama M, Ushikubi F, Kobayashi T, Hirata M, Sugimoto Y, Narumiya S: Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1997 Sep;122(2):217-24.@@Nataraj C, Thomas DW, Tilley SL, Nguyen MT, Mannon R, Koller BH, Coffman TM: Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse. J Clin Invest. 2001 Oct;108(8):1229-35.@@Crider JY, Xu SX, Sharif NA: Pharmacology of functional endogenous IP prostanoid receptors in NCB-20 cells: comparison with binding data from human platelets. Prostaglandins Leukot Essent Fatty Acids. 2001 Nov-Dec;65(5-6):253-8. |
| Groups | Approved |
| Direct Classification | Prostaglandins and related compounds |
| SMILES | CCCCC(C)(O)CC=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC |
| Pathways | |
| PharmGKB | PA450523 |
| ChEMBL | CHEMBL606 |
