| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10012333 | HBV | ENSG00000171522.6 | protein_coding | PTGER4 | No | No | 5734 | A0PJF5 P35408 |
| TVIS44000241 | HTLV-1 | ENSG00000171522.6 | protein_coding | PTGER4 | No | No | 5734 | A0PJF5 P35408 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PTGER4 |
|---|---|
| DrugBank ID | DB12836 |
| Drug Name | Grapiprant |
| Target ID | BE0003522 |
| UniProt ID | P35408 |
| Regulation Type | antagonist |
| PubMed IDs | 29067176; 21752876 |
| Citations | Kirkby Shaw K, Rausch-Derra LC, Rhodes L: Grapiprant: an EP4 prostaglandin receptor antagonist and novel therapy for pain and inflammation. Vet Med Sci. 2015 Dec 21;2(1):3-9. doi: 10.1002/vms3.13. eCollection 2016 Feb.@@Woodward DF, Jones RL, Narumiya S: International Union of Basic and Clinical Pharmacology. LXXXIII: classification of prostanoid receptors, updating 15 years of progress. Pharmacol Rev. 2011 Sep;63(3):471-538. doi: 10.1124/pr.110.003517. Epub 2011 Jul 13. |
| Groups | Investigational; Vet_approved |
| Direct Classification | Phenylimidazoles |
| SMILES | CCC1=NC2=C(C)N=C(C)C=C2N1C1=CC=C(CCNC(=O)NS(=O)(=O)C2=CC=C(C)C=C2)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3039498 |
