| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10033171 | HBV | ENSG00000096717.12 | protein_coding | SIRT1 | No | No | 23411 | B0QZ35 E9PC49 Q96EB6 |
| TVIS44035877 | HTLV-1 | ENSG00000096717.12 | protein_coding | SIRT1 | No | No | 23411 | B0QZ35 E9PC49 Q96EB6 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | SIRT1 |
|---|---|
| DrugBank ID | DB15493 |
| Drug Name | Cambinol |
| Target ID | BE0002461 |
| UniProt ID | Q96EB6 |
| Regulation Type | inhibitor |
| PubMed IDs | 16618762 |
| Citations | Heltweg B, Gatbonton T, Schuler AD, Posakony J, Li H, Goehle S, Kollipara R, Depinho RA, Gu Y, Simon JA, Bedalov A: Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Cancer Res. 2006 Apr 15;66(8):4368-77. doi: 10.1158/0008-5472.CAN-05-3617. |
| Groups | Experimental |
| Direct Classification | |
| SMILES | OC1=C(CC2=C(NC(=S)NC2=O)C2=CC=CC=C2)C2=CC=CC=C2C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL491960 |
