| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10033171 | HBV | ENSG00000096717.12 | protein_coding | SIRT1 | No | No | 23411 | B0QZ35 E9PC49 Q96EB6 |
| TVIS44035877 | HTLV-1 | ENSG00000096717.12 | protein_coding | SIRT1 | No | No | 23411 | B0QZ35 E9PC49 Q96EB6 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SIRT1 |
|---|---|
| DrugBank ID | DB02709 |
| Drug Name | Resveratrol |
| Target ID | BE0002461 |
| UniProt ID | Q96EB6 |
| Regulation Type | |
| PubMed IDs | 23524286; 23471411 |
| Citations | Lakshminarasimhan M, Rauh D, Schutkowski M, Steegborn C: Sirt1 activation by resveratrol is substrate sequence-selective. Aging (Albany NY). 2013 Mar;5(3):151-4. doi: 10.18632/aging.100542.@@Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, Pentelute BL, Schuman ER, Stevens LA, Ling AJ, Armour SM, Michan S, Zhao H, Jiang Y, Sweitzer SM, Blum CA, Disch JS, Ng PY, Howitz KT, Rolo AP, Hamuro Y, Moss J, Perni RB, Ellis JL, Vlasuk GP, Sinclair DA: Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science. 2013 Mar 8;339(6124):1216-9. doi: 10.1126/science.1231097. |
| Groups | Investigational |
| Direct Classification | Stilbenes |
| SMILES | OC1=CC=C(C=CC2=CC(O)=CC(O)=C2)C=C1 |
| Pathways | |
| PharmGKB | PA165291838 |
| ChEMBL | CHEMBL165 |
