| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30020280 | HIV | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
| TVIS30041206 | HIV | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
| TVIS20052523 | HPV | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
| TVIS20052711 | HPV | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
| TVIS44027356 | HTLV-1 | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
| TVIS44005056 | HTLV-1 | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TK2 |
|---|---|
| DrugBank ID | DB03312 |
| Drug Name | Brivudine |
| Target ID | BE0004639 |
| UniProt ID | O00142 |
| Regulation Type | substrate |
| PubMed IDs | 16630572 |
| Citations | Franzolin E, Rampazzo C, Perez-Perez MJ, Hernandez AI, Balzarini J, Bianchi V: Bromovinyl-deoxyuridine: A selective substrate for mitochondrial thymidine kinase in cell extracts. Biochem Biophys Res Commun. 2006 May 26;344(1):30-6. doi: 10.1016/j.bbrc.2006.03.147. |
| Groups | Approved; Investigational |
| Direct Classification | Pyrimidine 2'-deoxyribonucleosides |
| SMILES | OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(C=CBr)C(=O)NC1=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL31634 |
