| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30020280 | HIV | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
| TVIS30041206 | HIV | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
| TVIS20052523 | HPV | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
| TVIS20052711 | HPV | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
| TVIS44027356 | HTLV-1 | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
| TVIS44005056 | HTLV-1 | ENSG00000166548.17 | protein_coding | TK2 | No | No | 7084 | A4IF54 A5PLM0 O00142 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TK2 |
|---|---|
| DrugBank ID | DB04485 |
| Drug Name | Thymidine |
| Target ID | BE0004639 |
| UniProt ID | O00142 |
| Regulation Type | substrate |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental; Investigational |
| Direct Classification | Pyrimidine 2'-deoxyribonucleosides |
| SMILES | CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O |
| Pathways | UMP Synthase Deficiency (Orotic Aciduria); MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy); Dihydropyrimidinase Deficiency; beta-Ureidopropionase Deficiency; Pyrimidine Metabolism |
| PharmGKB | |
| ChEMBL | CHEMBL52609 |
