| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30082168 | HIV | ENSG00000184012.14 | protein_coding | TMPRSS2 | No | No | 7113 | O15393 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TMPRSS2 |
|---|---|
| DrugBank ID | DB16737 |
| Drug Name | MM3122 |
| Target ID | BE0009920 |
| UniProt ID | O15393 |
| Regulation Type | inhibitor |
| PubMed IDs | 34635581 |
| Citations | Mahoney M, Damalanka VC, Tartell MA, Chung DH, Lourenco AL, Pwee D, Mayer Bridwell AE, Hoffmann M, Voss J, Karmakar P, Azouz NP, Klingler AM, Rothlauf PW, Thompson CE, Lee M, Klampfer L, Stallings CL, Rothenberg ME, Pohlmann S, Whelan SPJ, O'Donoghue AJ, Craik CS, Janetka JW: A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43). pii: 2108728118. doi: 10.1073/pnas.2108728118. |
| Groups | Experimental |
| Direct Classification | |
| SMILES | CC(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)C1=NC2=CC=CC=C2S1 |
| Pathways | |
| PharmGKB | |
| ChEMBL |
