| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018416 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10019591 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10050130 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060226 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060735 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060227 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060228 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060225 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10062340 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060224 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TTR |
|---|---|
| DrugBank ID | DB11644 |
| Drug Name | Tafamidis |
| Target ID | BE0000337 |
| UniProt ID | P02766 |
| Regulation Type | chaperone |
| PubMed IDs | 31735731 |
| Citations | Endo J, Sano M, Izumiya Y, Tsujita K, Nakamura K, Tahara N, Kuwahara K, Inomata T, Ueda M, Sekijima Y, Ando Y, Tsutsui H, Isobe M, Fukuda K: A Statement on the Appropriate Administration of Tafamidis in Patients With Transthyretin Cardiac Amyloidosis. Circ J. 2019 Dec 25;84(1):15-17. doi: 10.1253/circj.CJ-19-0811. Epub 2019 Nov 16. |
| Groups | Approved; Investigational |
| Direct Classification | Phenyl-1,3-oxazoles |
| SMILES | OC(=O)C1=CC=C2N=C(OC2=C1)C1=CC(Cl)=CC(Cl)=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2103837 |
