| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018416 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10019591 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10050130 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060226 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060735 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060227 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060228 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060225 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10062340 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
| TVIS10060224 | HBV | ENSG00000118271.12 | protein_coding | TTR | No | No | 7276 | P02766 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TTR |
|---|---|
| DrugBank ID | DB16309 |
| Drug Name | Revusiran |
| Target ID | BE0000337 |
| UniProt ID | P02766 |
| Regulation Type | regulator |
| PubMed IDs | 32062791 |
| Citations | Judge DP, Kristen AV, Grogan M, Maurer MS, Falk RH, Hanna M, Gillmore J, Garg P, Vaishnaw AK, Harrop J, Powell C, Karsten V, Zhang X, Sweetser MT, Vest J, Hawkins PN: Phase 3 Multicenter Study of Revusiran in Patients with Hereditary Transthyretin-Mediated (hATTR) Amyloidosis with Cardiomyopathy (ENDEAVOUR). Cardiovasc Drugs Ther. 2020 Jun;34(3):357-370. doi: 10.1007/s10557-019-06919-4. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |
