Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10008216HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10026116HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10048269HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10048270HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10052479HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10052709HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS30084289HIVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS30088779HIVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS30018326HIVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS30026961HIVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TCGA Plot Options
Drug Information
GeneCHRM3
DrugBank IDDB00940
Drug NameMethantheline
Target IDBE0000045
UniProt IDP20309
Regulation Type
PubMed IDs17922784; 29938305
CitationsAbrams P, Andersson KE: Muscarinic receptor antagonists for overactive bladder. BJU Int. 2007 Nov;100(5):987-1006. doi: 10.1111/j.1464-410X.2007.07205.x.@@Irmen M, Holze J, Bodefeld T, Trankle C: Characterization of methanthelinium binding and function at human M1-M5 muscarinic acetylcholine receptors. Naunyn Schmiedebergs Arch Pharmacol. 2018 Oct;391(10):1037-1052. doi: 10.1007/s00210-018-1525-1. Epub 2018 Jun 24.
GroupsApproved; Investigational
Direct ClassificationXanthenes
SMILESCC[N+](C)(CC)CCOC(=O)C1C2=CC=CC=C2OC2=CC=CC=C12
Pathways
PharmGKBPA164747037
ChEMBLCHEMBL1201264