Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10008216HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10026116HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10048269HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10048270HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10052479HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10052709HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS30084289HIVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS30088779HIVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS30018326HIVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS30026961HIVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TCGA Plot Options
Drug Information
GeneCHRM3
DrugBank IDDB09076
Drug NameUmeclidinium
Target IDBE0000045
UniProt IDP20309
Regulation Typeantagonist
PubMed IDs23435542
CitationsSalmon M, Luttmann MA, Foley JJ, Buckley PT, Schmidt DB, Burman M, Webb EF, DeHaas CJ, Kotzer CJ, Barrett VJ, Slack RJ, Sarau HM, Palovich MR, Laine DI, Hay DW, Rumsey WL: Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases. J Pharmacol Exp Ther. 2013 May;345(2):260-70. doi: 10.1124/jpet.112.202051. Epub 2013 Feb 22.
GroupsApproved
Direct ClassificationDiphenylmethanes
SMILESOC(C1=CC=CC=C1)(C1=CC=CC=C1)C12CC[N+](CCOCC3=CC=CC=C3)(CC1)CC2
Pathways
PharmGKB
ChEMBLCHEMBL1187833