| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30018466 | HIV | ENSG00000087586.18 | protein_coding | AURKA | Yes | No | 6790 | O14965 |
| TVIS30053969 | HIV | ENSG00000087586.18 | protein_coding | AURKA | Yes | No | 6790 | O14965 |
| TVIS44033120 | HTLV-1 | ENSG00000087586.18 | protein_coding | AURKA | Yes | No | 6790 | O14965 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AURKA |
|---|---|
| DrugBank ID | DB05220 |
| Drug Name | Alisertib |
| Target ID | BE0000991 |
| UniProt ID | O14965 |
| Regulation Type | inhibitor |
| PubMed IDs | 26732741 |
| Citations | de Groot CO, Hsia JE, Anzola JV, Motamedi A, Yoon M, Wong YL, Jenkins D, Lee HJ, Martinez MB, Davis RL, Gahman TC, Desai A, Shiau AK: A Cell Biologist's Field Guide to Aurora Kinase Inhibitors. Front Oncol. 2015 Dec 21;5:285. doi: 10.3389/fonc.2015.00285. eCollection 2015. |
| Groups | Investigational |
| Direct Classification | Benzazepines |
| SMILES | COC1=CC(NC2=NC=C3CN=C(C4=CC(Cl)=CC=C4C3=N2)C2=C(OC)C=CC=C2F)=CC=C1C(O)=O |
| Pathways | |
| PharmGKB | PA166165015 |
| ChEMBL | CHEMBL483158 |
