| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017602 | HBV | ENSG00000160868.16 | protein_coding | CYP3A4 | No | No | 1576 | P08684 Q6GRK0 |
| TVIS10009001 | HBV | ENSG00000160868.16 | protein_coding | CYP3A4 | No | No | 1576 | P08684 Q6GRK0 |
| TVIS10019432 | HBV | ENSG00000160868.16 | protein_coding | CYP3A4 | No | No | 1576 | P08684 Q6GRK0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CYP3A4 |
|---|---|
| DrugBank ID | DB06634 |
| Drug Name | Casopitant |
| Target ID | BE0002638 |
| UniProt ID | P08684 |
| Regulation Type | |
| PubMed IDs | 21149541 |
| Citations | Motta P, Pons N, Pagliarusco S, Pellegatti M, Bonomo F: Casopitant: in vitro data and SimCyp simulation to predict in vivo metabolic interactions involving cytochrome P450 3A4. Drug Metab Dispos. 2011 Mar;39(3):363-72. doi: 10.1124/dmd.110.035071. Epub 2010 Dec 13. |
| Groups | Investigational |
| Direct Classification | Phenylpiperidines |
| SMILES | C[C@@H](N(C)C(=O)N1CC[C@@H](C[C@@H]1C1=CC=C(F)C=C1C)N1CCN(CC1)C(C)=O)C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F |
| Pathways | |
| PharmGKB | PA166129533 |
| ChEMBL | CHEMBL1672054 |
