| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20005075 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20070128 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20021184 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20013131 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20021370 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20013130 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20015735 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20015651 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20021366 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20070129 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ERBB2 |
|---|---|
| DrugBank ID | DB05773 |
| Drug Name | Trastuzumab emtansine |
| Target ID | BE0000511 |
| UniProt ID | P04626 |
| Regulation Type | antibody |
| PubMed IDs | 23196784; 19010901; 11752352 |
| Citations | Barginear MF, John V, Budman DR: Trastuzumab-DM1: a clinical update of the novel antibody-drug conjugate for HER2-overexpressing breast cancer. Mol Med. 2013 Jan 22;18:1473-9. doi: 10.2119/molmed.2012.00302.@@Lewis Phillips GD, Li G, Dugger DL, Crocker LM, Parsons KL, Mai E, Blattler WA, Lambert JM, Chari RV, Lutz RJ, Wong WL, Jacobson FS, Koeppen H, Schwall RH, Kenkare-Mitra SR, Spencer SD, Sliwkowski MX: Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate. Cancer Res. 2008 Nov 15;68(22):9280-90. doi: 10.1158/0008-5472.CAN-08-1776.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1743082 |
