| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20011676 | HPV | ENSG00000152578.15 | protein_coding | GRIA4 | No | No | 2893 | P48058 Q1WWK6 |
| TVIS20049996 | HPV | ENSG00000152578.15 | protein_coding | GRIA4 | No | No | 2893 | P48058 Q1WWK6 |
| TVIS20027241 | HPV | ENSG00000152578.15 | protein_coding | GRIA4 | No | No | 2893 | P48058 Q1WWK6 |
| TVIS44030164 | HTLV-1 | ENSG00000152578.15 | protein_coding | GRIA4 | No | No | 2893 | P48058 Q1WWK6 |
| TVIS44049369 | HTLV-1 | ENSG00000152578.15 | protein_coding | GRIA4 | No | No | 2893 | P48058 Q1WWK6 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRIA4 |
|---|---|
| DrugBank ID | DB04982 |
| Drug Name | Talampanel |
| Target ID | BE0000830 |
| UniProt ID | P48058 |
| Regulation Type | |
| PubMed IDs | 12581229; 17199027; 16861112 |
| Citations | Langan YM, Lucas R, Jewell H, Toublanc N, Schaefer H, Sander JW, Patsalos PN: Talampanel, a new antiepileptic drug: single- and multiple-dose pharmacokinetics and initial 1-week experience in patients with chronic intractable epilepsy. Epilepsia. 2003 Jan;44(1):46-53.@@Howes JF, Bell C: Talampanel. Neurotherapeutics. 2007 Jan;4(1):126-9.@@Denes L, Szilagyi G, Gal A, Nagy Z: Talampanel a non-competitive AMPA-antagonist attenuates caspase-3 dependent apoptosis in mouse brain after transient focal cerebral ischemia. Brain Res Bull. 2006 Jul 31;70(3):260-2. Epub 2006 Mar 31. |
| Groups | Investigational |
| Direct Classification | Benzodiazepines |
| SMILES | C[C@@H]1CC2=CC3=C(OCO3)C=C2C(=NN1C(C)=O)C1=CC=C(N)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL61872 |
