Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30001525HIVENSG00000182866.18protein_codingLCKYesNo3932A0A0S2Z3Y4
A0A0S2Z3Y8
P06239
Q573B4
TVIS30001526HIVENSG00000182866.18protein_codingLCKYesNo3932A0A0S2Z3Y4
A0A0S2Z3Y8
P06239
Q573B4
TVIS30001527HIVENSG00000182866.18protein_codingLCKYesNo3932A0A0S2Z3Y4
A0A0S2Z3Y8
P06239
Q573B4
TVIS30005158HIVENSG00000182866.18protein_codingLCKYesNo3932A0A0S2Z3Y4
A0A0S2Z3Y8
P06239
Q573B4
TVIS30005159HIVENSG00000182866.18protein_codingLCKYesNo3932A0A0S2Z3Y4
A0A0S2Z3Y8
P06239
Q573B4
TVIS30001528HIVENSG00000182866.18protein_codingLCKYesNo3932A0A0S2Z3Y4
A0A0S2Z3Y8
P06239
Q573B4
TVIS30011230HIVENSG00000182866.18protein_codingLCKYesNo3932A0A0S2Z3Y4
A0A0S2Z3Y8
P06239
Q573B4
TVIS30011231HIVENSG00000182866.18protein_codingLCKYesNo3932A0A0S2Z3Y4
A0A0S2Z3Y8
P06239
Q573B4
TVIS30081084HIVENSG00000182866.18protein_codingLCKYesNo3932A0A0S2Z3Y4
A0A0S2Z3Y8
P06239
Q573B4
TVIS30023044HIVENSG00000182866.18protein_codingLCKYesNo3932A0A0S2Z3Y4
A0A0S2Z3Y8
P06239
Q573B4
TCGA Plot Options
Drug Information
GeneLCK
DrugBank IDDB03023
Drug Name1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
Target IDBE0000842
UniProt IDP06239
Regulation Type
PubMed IDs17139284; 17016423; 10592235
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsExperimental
Direct ClassificationPhenylpyrazoles
SMILESCC(C)(C)N1[NH+]=C(C2=C1N=CN=C2N)C1=CC=C(Cl)C=C1
Pathways
PharmGKB
ChEMBL