Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44005531HTLV-1ENSG00000087245.13protein_codingMMP2NoNo4313P08253
TVIS44036049HTLV-1ENSG00000087245.13protein_codingMMP2NoNo4313P08253
TCGA Plot Options
Drug Information
GeneMMP2
DrugBank IDDB04866
Drug NameHalofuginone
Target IDBE0000642
UniProt IDP08253
Regulation Type
PubMed IDs11099465
CitationsElkin M, Miao HQ, Nagler A, Aingorn E, Reich R, Hemo I, Dou HL, Pines M, Vlodavsky I: Halofuginone: a potent inhibitor of critical steps in angiogenesis progression. FASEB J. 2000 Dec;14(15):2477-85.
GroupsInvestigational; Vet_approved
Direct ClassificationQuinazolines
SMILES[H][C@]1(O)CCCN[C@]1([H])CC(=O)CN1C=NC2=C(C=C(Cl)C(Br)=C2)C1=O
Pathways
PharmGKB
ChEMBLCHEMBL1199540