| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44005531 | HTLV-1 | ENSG00000087245.13 | protein_coding | MMP2 | No | No | 4313 | P08253 |
| TVIS44036049 | HTLV-1 | ENSG00000087245.13 | protein_coding | MMP2 | No | No | 4313 | P08253 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MMP2 |
|---|---|
| DrugBank ID | DB12843 |
| Drug Name | Oleandrin |
| Target ID | BE0000642 |
| UniProt ID | P08253 |
| Regulation Type | inhibitor |
| PubMed IDs | 26444270 |
| Citations | Ma Y, Zhu B, Liu X, Yu H, Yong L, Liu X, Shao J, Liu Z: Inhibition of oleandrin on the proliferation show and invasion of osteosarcoma cells in vitro by suppressing Wnt/beta-catenin signaling pathway. J Exp Clin Cancer Res. 2015 Oct 6;34:115. doi: 10.1186/s13046-015-0232-8. |
| Groups | Experimental; Investigational |
| Direct Classification | Cardenolide glycosides and derivatives |
| SMILES | CO[C@H]1C[C@H](O[C@H]2CC[C@@]3(C)[C@H](CC[C@@H]4[C@@H]3CC[C@]3(C)[C@H]([C@H](C[C@]43O)OC(C)=O)C3=CC(=O)OC3)C2)O[C@@H](C)[C@@H]1O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1075789 |
