Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20011855HPVENSG00000134640.3protein_codingMTNR1BNoNo4544P49286
TCGA Plot Options
Drug Information
GeneMTNR1B
DrugBank IDDB06594
Drug NameAgomelatine
Target IDBE0000327
UniProt IDP49286
Regulation Typeagonist
PubMed IDs15289999
CitationsMillan MJ, Brocco M, Gobert A, Dekeyne A: Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade. Psychopharmacology (Berl). 2005 Feb;177(4):448-58. Epub 2004 Jul 31.
GroupsApproved; Investigational
Direct ClassificationN-acetyl-2-arylethylamines
SMILESCOC1=CC2=C(CCNC(C)=O)C=CC=C2C=C1
Pathways
PharmGKBPA165958363
ChEMBLCHEMBL10878