Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20059608HPVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS20015845HPVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS20015825HPVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS20022834HPVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS20037383HPVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS20059796HPVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS20024119HPVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS20059195HPVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS20024155HPVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS20024283HPVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TCGA Plot Options
Drug Information
GenePDE4D
DrugBank IDDB01791
Drug NamePiclamilast
Target IDBE0001287
UniProt IDQ08499
Regulation Type
PubMed IDs15765929; 10592235
CitationsBeeh KM, Beier J, Lerch C, Schulz AK, Buhl R: Effects of piclamilast, a selective phosphodiesterase-4 inhibitor, on oxidative burst of sputum cells from mild asthmatics and stable COPD patients. Lung. 2004;182(6):369-77.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsExperimental
Direct ClassificationBenzamides
SMILESCOC1=CC=C(C=C1OC1CCCC1)C(=O)NC1=C(Cl)C=NC=C1Cl
Pathways
PharmGKB
ChEMBLCHEMBL42126