| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018686 | HBV | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS10043244 | HBV | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS30003460 | HIV | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS30003461 | HIV | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS30056264 | HIV | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS30056265 | HIV | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS30056266 | HIV | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS20008281 | HPV | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS20057660 | HPV | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
| TVIS20032514 | HPV | ENSG00000132170.24 | protein_coding | PPARG | Yes | No | 5468 | D2KUA6 E9PFX5 P37231 Q4W448 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PPARG |
|---|---|
| DrugBank ID | DB00244 |
| Drug Name | Mesalazine |
| Target ID | BE0000215 |
| UniProt ID | P37231 |
| Regulation Type | agonist |
| PubMed IDs | 15824083; 18544567; 18077625; 16939423 |
| Citations | Rousseaux C, Lefebvre B, Dubuquoy L, Lefebvre P, Romano O, Auwerx J, Metzger D, Wahli W, Desvergne B, Naccari GC, Chavatte P, Farce A, Bulois P, Cortot A, Colombel JF, Desreumaux P: Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma. J Exp Med. 2005 Apr 18;201(8):1205-15. Epub 2005 Apr 11.@@Schwab M, Reynders V, Loitsch S, Shastri YM, Steinhilber D, Schroder O, Stein J: PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells. Carcinogenesis. 2008 Jul;29(7):1407-14. doi: 10.1093/carcin/bgn118. Epub 2008 Jun 9.@@Linard C, Gremy O, Benderitter M: Reduction of peroxisome proliferation-activated receptor gamma expression by gamma-irradiation as a mechanism contributing to inflammatory response in rat colon: modulation by the 5-aminosalicylic acid agonist. J Pharmacol Exp Ther. 2008 Mar;324(3):911-20. Epub 2007 Dec 12.@@Desreumaux P, Ghosh S: Review article: mode of action and delivery of 5-aminosalicylic acid - new evidence. Aliment Pharmacol Ther. 2006 Sep;24 Suppl 1:2-9. |
| Groups | Approved |
| Direct Classification | Aminobenzoic acids |
| SMILES | NC1=CC(C(O)=O)=C(O)C=C1 |
| Pathways | |
| PharmGKB | PA450384 |
| ChEMBL | CHEMBL704 |
