Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10018748HBVENSG00000080824.19protein_codingHSP90AA1YesNo3320P07900
TVIS30037413HIVENSG00000080824.19protein_codingHSP90AA1YesNo3320P07900
TVIS30037414HIVENSG00000080824.19protein_codingHSP90AA1YesNo3320P07900
TVIS20052009HPVENSG00000080824.19protein_codingHSP90AA1YesNo3320P07900
TVIS20030653HPVENSG00000080824.19protein_codingHSP90AA1YesNo3320P07900
TVIS44033980HTLV-1ENSG00000080824.19protein_codingHSP90AA1YesNo3320P07900
TCGA Plot Options
Drug Information
GeneHSP90AA1
DrugBank IDDB12442
Drug NameAlvespimycin
Target IDBE0001120
UniProt IDP07900
Regulation Typeinhibitor
PubMed IDs17139284; 17016423; 10592235
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsInvestigational
Direct ClassificationMacrolactams
SMILESCO[C@H]1C[C@H](C)CC2=C(NCCN(C)C)C(=O)C=C(NC(=O)C(C)=CC=C/[C@H](OC)[C@@H](OC(N)=O)C(C)=C[C@H](C)[C@H]1O)C2=O
Pathways
PharmGKB
ChEMBLCHEMBL383824