| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30087724 | HIV | ENSG00000108878.5 | protein_coding | CACNG1 | No | No | 786 | Q06432 |
| TVIS30044813 | HIV | ENSG00000108878.5 | protein_coding | CACNG1 | No | No | 786 | Q06432 |
| TVIS20036507 | HPV | ENSG00000108878.5 | protein_coding | CACNG1 | No | No | 786 | Q06432 |
| TVIS44023880 | HTLV-1 | ENSG00000108878.5 | protein_coding | CACNG1 | No | No | 786 | Q06432 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNG1 |
|---|---|
| DrugBank ID | DB00528 |
| Drug Name | Lercanidipine |
| Target ID | BE0000679 |
| UniProt ID | Q06432 |
| Regulation Type | inhibitor |
| PubMed IDs | 17139284; 17016423; 19619074 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Burnier M, Pruijm M, Wuerzner G: Treatment of essential hypertension with calcium channel blockers: what is the place of lercanidipine? Expert Opin Drug Metab Toxicol. 2009 Aug;5(8):981-7. doi: 10.1517/17425250903085135. |
| Groups | Approved; Investigational |
| Direct Classification | Diphenylmethanes |
| SMILES | COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC(C)(C)CN(C)CCC(C1=CC=CC=C1)C1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA164769058 |
| ChEMBL | CHEMBL250270 |