| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44013570 | HTLV-1 | ENSG00000159110.22 | protein_coding | IFNAR2 | No | No | 3455 | P48551 Q9BUA0 |
| TVIS44011234 | HTLV-1 | ENSG00000159110.22 | protein_coding | IFNAR2 | No | No | 3455 | P48551 Q9BUA0 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | IFNAR2 |
|---|---|
| DrugBank ID | DB00034 |
| Drug Name | Interferon alfa-2a |
| Target ID | BE0000385 |
| UniProt ID | P48551 |
| Regulation Type | |
| PubMed IDs | 15898717; 18230610 |
| Citations | Dhalluin C, Ross A, Huber W, Gerber P, Brugger D, Gsell B, Senn H: Structural, kinetic, and thermodynamic analysis of the binding of the 40 kDa PEG-interferon-alpha2a and its individual positional isomers to the extracellular domain of the receptor IFNAR2. Bioconjug Chem. 2005 May-Jun;16(3):518-27.@@Cironi P, Swinburne IA, Silver PA: Enhancement of cell type specificity by quantitative modulation of a chimeric ligand. J Biol Chem. 2008 Mar 28;283(13):8469-76. doi: 10.1074/jbc.M708502200. Epub 2008 Jan 29. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA164779048 |
| ChEMBL |
