| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44013570 | HTLV-1 | ENSG00000159110.22 | protein_coding | IFNAR2 | No | No | 3455 | P48551 Q9BUA0 |
| TVIS44011234 | HTLV-1 | ENSG00000159110.22 | protein_coding | IFNAR2 | No | No | 3455 | P48551 Q9BUA0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | IFNAR2 |
|---|---|
| DrugBank ID | DB00060 |
| Drug Name | Interferon beta-1a |
| Target ID | BE0000385 |
| UniProt ID | P48551 |
| Regulation Type | |
| PubMed IDs | 16912135; 11747625 |
| Citations | van Koetsveld PM, Vitale G, de Herder WW, Feelders RA, van der Wansem K, Waaijers M, van Eijck CH, Speel EJ, Croze E, van der Lely AJ, Lamberts SW, Hofland LJ: Potent inhibitory effects of type I interferons on human adrenocortical carcinoma cell growth. J Clin Endocrinol Metab. 2006 Nov;91(11):4537-43. Epub 2006 Aug 15.@@Runkel L, De Dios C, Karpusas M, Baker D, Li Z, Zafari M, Betzenhauser M, Muldowney C, Miller S, Redlich PN, Grossberg SE, Whitty A, Hochman PS: Mapping of IFN-beta epitopes important for receptor binding and biologic activation: comparison of results achieved using antibody-based methods and alanine substitution mutagenesis. J Interferon Cytokine Res. 2001 Nov;21(11):931-41. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA450037 |
| ChEMBL | CHEMBL1201562 |
