Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10006502HBVENSG00000138039.15protein_codingLHCGRNoNo3973P22888
TVIS30017091HIVENSG00000138039.15protein_codingLHCGRNoNo3973P22888
TVIS20010110HPVENSG00000138039.15protein_codingLHCGRNoNo3973P22888
TVIS20067968HPVENSG00000138039.15protein_codingLHCGRNoNo3973P22888
TVIS20032707HPVENSG00000138039.15protein_codingLHCGRNoNo3973P22888
TCGA Plot Options
Drug Information
GeneLHCGR
DrugBank IDDB00097
Drug NameChoriogonadotropin alfa
Target IDBE0000134
UniProt IDP22888
Regulation Type
PubMed IDs15967102; 12606382; 17059863
CitationsBodek G, Vierre S, Rivero-Muller A, Huhtaniemi I, Ziecik AJ, Rahman NA: A novel targeted therapy of Leydig and granulosa cell tumors through the luteinizing hormone receptor using a hecate-chorionic gonadotropin beta conjugate in transgenic mice. Neoplasia. 2005 May;7(5):497-508.@@Gromoll J, Wistuba J, Terwort N, Godmann M, Muller T, Simoni M: A new subclass of the luteinizing hormone/chorionic gonadotropin receptor lacking exon 10 messenger RNA in the New World monkey (Platyrrhini) lineage. Biol Reprod. 2003 Jul;69(1):75-80. Epub 2003 Feb 19.@@Lin W, Bernard MP, Cao D, Myers RV, Kerrigan JE, Moyle WR: Follitropin receptors contain cryptic ligand binding sites. Mol Cell Endocrinol. 2007 Jan 2;260-262:83-92. Epub 2006 Oct 23.
GroupsApproved
Direct ClassificationPeptides
SMILES
Pathways
PharmGKBPA164783947
ChEMBLCHEMBL1201464