| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017505 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10018413 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10016567 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10016094 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10019538 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS30083084 | HIV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS30032260 | HIV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS30032261 | HIV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS30032262 | HIV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS20005530 | HPV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE3A |
|---|---|
| DrugBank ID | DB01166 |
| Drug Name | Cilostazol |
| Target ID | BE0000436 |
| UniProt ID | Q14432 |
| Regulation Type | inhibitor |
| PubMed IDs | 11752352; 16472148; 12180353; 19218671; 18282775 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Hong KW, Lee JH, Kima KY, Park SY, Lee WS: Cilostazol: therapeutic potential against focal cerebral ischemic damage. Curr Pharm Des. 2006;12(5):565-73.@@Schror K: The pharmacology of cilostazol. Diabetes Obes Metab. 2002 Mar;4 Suppl 2:S14-9.@@Mokry J, Mokra D, Nosalova G, Beharkova M, Feherova Z: Influence of selective inhibitors of phosphodiesterase 3 and 4 on cough and airway reactivity. J Physiol Pharmacol. 2008 Dec;59 Suppl 6:473-82.@@Parkkonen J, Hasala H, Moilanen E, Giembycz MA, Kankaanranta H: Phosphodiesterase 4 inhibitors delay human eosinophil and neutrophil apoptosis in the absence and presence of salbutamol. Pulm Pharmacol Ther. 2008;21(3):499-506. doi: 10.1016/j.pupt.2007.11.003. Epub 2007 Nov 22. |
| Groups | Approved; Investigational |
| Direct Classification | Hydroquinolones |
| SMILES | O=C1CCC2=C(N1)C=CC(OCCCCC1=NN=NN1C1CCCCC1)=C2 |
| Pathways | Cilostazol Action Pathway |
| PharmGKB | PA164746334 |
| ChEMBL | CHEMBL799 |
