| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017505 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10018413 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10016567 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10016094 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10019538 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS30083084 | HIV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS30032260 | HIV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS30032261 | HIV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS30032262 | HIV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS20005530 | HPV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE3A |
|---|---|
| DrugBank ID | DB01303 |
| Drug Name | Oxtriphylline |
| Target ID | BE0000436 |
| UniProt ID | Q14432 |
| Regulation Type | inhibitor |
| PubMed IDs | 12887610; 15237094; 16651698 |
| Citations | Rickards KJ, Andrews MJ, Waterworth TH, Alexander GB, Cunningham FM: Differential effects of phosphodiesterase inhibitors on platelet activating factor (PAF)- and adenosine diphosphate (ADP)-induced equine platelet aggregation. J Vet Pharmacol Ther. 2003 Aug;26(4):277-82.@@Wu BN, Lin RJ, Lo YC, Shen KP, Wang CC, Lin YT, Chen IJ: KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels. Br J Pharmacol. 2004 Aug;142(7):1105-14. Epub 2004 Jul 5.@@Kajikawa S, Kigami D, Nakayama H, Doi K: Changes in submaxillary gland gene expression in F344 rats by multiple dosing of theophylline. Exp Anim. 2006 Apr;55(2):143-6. |
| Groups | Approved |
| Direct Classification | Xanthines |
| SMILES | C[N+](C)(C)CCO.CN1C2=C([N-]C=N2)C(=O)N(C)C1=O |
| Pathways | |
| PharmGKB | PA164748137 |
| ChEMBL | CHEMBL1200434 |
