| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30023985 | HIV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS20007444 | HPV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS20036920 | HPV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS20039414 | HPV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS20022219 | HPV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS20022256 | HPV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS20022231 | HPV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS20022242 | HPV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS20022221 | HPV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
| TVIS20022222 | HPV | ENSG00000184588.18 | protein_coding | PDE4B | No | No | 5142 | Q07343 X5DNX5 X5DR82 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE4B |
|---|---|
| DrugBank ID | DB00824 |
| Drug Name | Enprofylline |
| Target ID | BE0000487 |
| UniProt ID | Q07343 |
| Regulation Type | inhibitor |
| PubMed IDs | 27472311; 7680859 |
| Citations | Monteiro JP, Alves MG, Oliveira PF, Silva BM: Structure-Bioactivity Relationships of Methylxanthines: Trying to Make Sense of All the Promises and the Drawbacks. Molecules. 2016 Jul 27;21(8). pii: molecules21080974. doi: 10.3390/molecules21080974.@@Ukena D, Schudt C, Sybrecht GW: Adenosine receptor-blocking xanthines as inhibitors of phosphodiesterase isozymes. Biochem Pharmacol. 1993 Feb 24;45(4):847-51. |
| Groups | Approved; Experimental |
| Direct Classification | Xanthines |
| SMILES | CCCN1C2=C(NC=N2)C(=O)NC1=O |
| Pathways | |
| PharmGKB | PA164749350 |
| ChEMBL | CHEMBL279898 |
