| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30003686 | HIV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS30088900 | HIV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS30076730 | HIV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS30060933 | HIV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS30060934 | HIV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS20011880 | HPV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS20058749 | HPV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS44036219 | HTLV-1 | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | PDE5A |
|---|---|
| DrugBank ID | DB00975 |
| Drug Name | Dipyridamole |
| Target ID | BE0000182 |
| UniProt ID | O76074 |
| Regulation Type | inhibitor |
| PubMed IDs | 15672122; 16080974; 16886928; 17308037; 11752352 |
| Citations | Kulkarni SK, Patil CS: Phosphodiesterase 5 enzyme and its inhibitors: update on pharmacological and therapeutical aspects. Methods Find Exp Clin Pharmacol. 2004 Dec;26(10):789-99.@@Santini F, Casali G, Franchi G, Auriemma S, Lusini M, Barozzi L, Favaro A, Messina A, Mazzucco A: Hemodynamic effects of inhaled nitric oxide and phosphodiesterase inhibitor (dipyridamole) on secondary pulmonary hypertension following heart valve surgery in adults. Int J Cardiol. 2005 Aug 18;103(2):156-63.@@Kruuse C, Lassen LH, Iversen HK, Oestergaard S, Olesen J: Dipyridamole may induce migraine in patients with migraine without aura. Cephalalgia. 2006 Aug;26(8):925-33.@@Jackson EK, Ren J, Zacharia LC, Mi Z: Characterization of renal ecto-phosphodiesterase. J Pharmacol Exp Ther. 2007 May;321(2):810-5. Epub 2007 Feb 16.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Dialkylarylamines |
| SMILES | OCCN(CCO)C1=NC2=C(N=C(N=C2N2CCCCC2)N(CCO)CCO)C(=N1)N1CCCCC1 |
| Pathways | Dipyridamole (Antiplatelet) Action Pathway |
| PharmGKB | PA449367 |
| ChEMBL | CHEMBL932 |
