| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30003686 | HIV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS30088900 | HIV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS30076730 | HIV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS30060933 | HIV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS30060934 | HIV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS20011880 | HPV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS20058749 | HPV | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
| TVIS44036219 | HTLV-1 | ENSG00000138735.16 | protein_coding | PDE5A | No | No | 8654 | G5E9C5 O76074 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE5A |
|---|---|
| DrugBank ID | DB01972 |
| Drug Name | Guanosine-5'-Monophosphate |
| Target ID | BE0000182 |
| UniProt ID | O76074 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. |
| Groups | Experimental |
| Direct Classification | Purine ribonucleoside monophosphates |
| SMILES | NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 |
| Pathways | Clomocycline Action Pathway; Lesch-Nyhan Syndrome (LNS); Xanthinuria Type I; Josamycin Action Pathway; Gentamicin Action Pathway; Kanamycin Action Pathway; Purine Nucleoside Phosphorylase Deficiency; Azithromycin Action Pathway; Glutamate Metabolism; Adenine Phosphoribosyltransferase Deficiency (APRT); Clindamycin Action Pathway; Mercaptopurine Action Pathway; Clarithromycin Action Pathway; Xanthine Dehydrogenase Deficiency (Xanthinuria); Hyperinsulinism-Hyperammonemia Syndrome; Troleandomycin Action Pathway; Mitochondrial DNA Depletion Syndrome; Oxytetracycline Action Pathway; Tetracycline Action Pathway; Erythromycin Action Pathway; Netilmicin Action Pathway; Myoadenylate Deaminase Deficiency; Homocarnosinosis; Neomycin Action Pathway; Roxithromycin Action Pathway; Purine Metabolism; Arbekacin Action Pathway; Gout or Kelley-Seegmiller Syndrome; Adenylosuccinate Lyase Deficiency; Streptomycin Action Pathway |
| PharmGKB | |
| ChEMBL | CHEMBL283807 |
