| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30056468 | HIV | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS30056469 | HIV | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS30056470 | HIV | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS30056471 | HIV | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS20001736 | HPV | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS20018964 | HPV | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS20056614 | HPV | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS20056970 | HPV | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS20057260 | HPV | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS20056508 | HPV | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RARB |
|---|---|
| DrugBank ID | DB00799 |
| Drug Name | Tazarotene |
| Target ID | BE0000206 |
| UniProt ID | P10826 |
| Regulation Type | agonist |
| PubMed IDs | 12942109; 15102095; 9035701; 18034539 |
| Citations | Jones PH, Burnett RD, Fainaru I, Nadolny P, Walker P, Yu Z, Tang-Liu D, Ganesan TS, Talbot DC, Harris AL, Rustin GJ: A phase 1 study of tazarotene in adults with advanced cancer. Br J Cancer. 2003 Sep 1;89(5):808-15.@@Orlandi A, Bianchi L, Costanzo A, Campione E, Giusto Spagnoli L, Chimenti S: Evidence of increased apoptosis and reduced proliferation in basal cell carcinomas treated with tazarotene. J Invest Dermatol. 2004 Apr;122(4):1037-41.@@Chandraratna RA: Tazarotene--first of a new generation of receptor-selective retinoids. Br J Dermatol. 1996 Oct;135 Suppl 49:18-25.@@Arechalde A, Saurat JH: Management of psoriasis: the position of retinoid drugs. BioDrugs. 2000 May;13(5):327-33. |
| Groups | Approved; Investigational |
| Direct Classification | Retinoids |
| SMILES | CCOC(=O)C1=CN=C(C=C1)C#CC1=CC2=C(SCCC2(C)C)C=C1 |
| Pathways | |
| PharmGKB | PA164746821 |
| ChEMBL | CHEMBL1657 |
