Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS42001004EBVENSG00000140009.19protein_codingESR2NoNo2100Q92731
TVIS10045761HBVENSG00000140009.19protein_codingESR2NoNo2100Q92731
TVIS10045762HBVENSG00000140009.19protein_codingESR2NoNo2100Q92731
TVIS30036598HIVENSG00000140009.19protein_codingESR2NoNo2100Q92731
TVIS30036599HIVENSG00000140009.19protein_codingESR2NoNo2100Q92731
TVIS30036600HIVENSG00000140009.19protein_codingESR2NoNo2100Q92731
TVIS30036601HIVENSG00000140009.19protein_codingESR2NoNo2100Q92731
TVIS20017167HPVENSG00000140009.19protein_codingESR2NoNo2100Q92731
TVIS20051518HPVENSG00000140009.19protein_codingESR2NoNo2100Q92731
TVIS20034451HPVENSG00000140009.19protein_codingESR2NoNo2100Q92731
TCGA Plot Options
Drug Information
GeneESR2
DrugBank IDDB11674
Drug NameEquol
Target IDBE0000792
UniProt IDQ92731
Regulation Typeagonist
PubMed IDs15084758; 15883431
CitationsMueller SO, Simon S, Chae K, Metzler M, Korach KS: Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor alpha (ERalpha) and ERbeta in human cells. Toxicol Sci. 2004 Jul;80(1):14-25. Epub 2004 Apr 14.@@Setchell KD, Clerici C, Lephart ED, Cole SJ, Heenan C, Castellani D, Wolfe BE, Nechemias-Zimmer L, Brown NM, Lund TD, Handa RJ, Heubi JE: S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr. 2005 May;81(5):1072-9.
GroupsInvestigational
Direct ClassificationIsoflavanols
SMILESOC1=CC=C(C=C1)[C@H]1COC2=C(C1)C=CC(O)=C2
Pathways
PharmGKB
ChEMBLCHEMBL198877