Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30026962HIVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS30026963HIVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS20001445HPVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS20001070HPVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS20041095HPVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS20038300HPVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS20046168HPVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS20044845HPVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS20042956HPVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS20065709HPVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TCGA Plot Options
Drug Information
GeneCHRM3
DrugBank IDDB09076
Drug NameUmeclidinium
Target IDBE0000045
UniProt IDP20309
Regulation Typeantagonist
PubMed IDs23435542
CitationsSalmon M, Luttmann MA, Foley JJ, Buckley PT, Schmidt DB, Burman M, Webb EF, DeHaas CJ, Kotzer CJ, Barrett VJ, Slack RJ, Sarau HM, Palovich MR, Laine DI, Hay DW, Rumsey WL: Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases. J Pharmacol Exp Ther. 2013 May;345(2):260-70. doi: 10.1124/jpet.112.202051. Epub 2013 Feb 22.
GroupsApproved
Direct ClassificationDiphenylmethanes
SMILESOC(C1=CC=CC=C1)(C1=CC=CC=C1)C12CC[N+](CCOCC3=CC=CC=C3)(CC1)CC2
Pathways
PharmGKB
ChEMBLCHEMBL1187833