| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30055083 | HIV | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
| TVIS20014702 | HPV | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
| TVIS20014703 | HPV | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
| TVIS20014704 | HPV | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
| TVIS20025997 | HPV | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
| TVIS20034287 | HPV | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
| TVIS20014705 | HPV | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
| TVIS20014706 | HPV | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
| TVIS20014712 | HPV | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
| TVIS20014713 | HPV | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | COMT |
|---|---|
| DrugBank ID | DB03907 |
| Drug Name | N-[(E)-3-[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-nitrobenzamide |
| Target ID | BE0002089 |
| UniProt ID | P21964 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental |
| Direct Classification | 5'-deoxyribonucleosides |
| SMILES | [H]N([H])C1=C2N=CN([C@@H]3O[C@H](C=CCN([H])C(=O)C4=C(O)C(O)=CC(=C4)[N+]([O-])=O)[C@@H](O)[C@H]3O)C2=NC=N1 |
| Pathways | |
| PharmGKB | |
| ChEMBL |
