| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44029857 | HTLV-1 | ENSG00000183454.19 | protein_coding | GRIN2A | No | Yes | 2903 | Q12879 |
| TVIS44029075 | HTLV-1 | ENSG00000183454.19 | protein_coding | GRIN2A | No | Yes | 2903 | Q12879 |
| TVIS44001350 | HTLV-1 | ENSG00000183454.19 | protein_coding | GRIN2A | No | Yes | 2903 | Q12879 |
| TVIS44014323 | HTLV-1 | ENSG00000183454.19 | protein_coding | GRIN2A | No | Yes | 2903 | Q12879 |
| TVIS44014324 | HTLV-1 | ENSG00000183454.19 | protein_coding | GRIN2A | No | Yes | 2903 | Q12879 |
| TVIS44032271 | HTLV-1 | ENSG00000183454.19 | protein_coding | GRIN2A | No | Yes | 2903 | Q12879 |
| TVIS44017860 | HTLV-1 | ENSG00000183454.19 | protein_coding | GRIN2A | No | Yes | 2903 | Q12879 |
| TVIS44051295 | HTLV-1 | ENSG00000183454.19 | protein_coding | GRIN2A | No | Yes | 2903 | Q12879 |
| TVIS44042004 | HTLV-1 | ENSG00000183454.19 | protein_coding | GRIN2A | No | Yes | 2903 | Q12879 |
| TVIS44042003 | HTLV-1 | ENSG00000183454.19 | protein_coding | GRIN2A | No | Yes | 2903 | Q12879 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | GRIN2A |
|---|---|
| DrugBank ID | DB06151 |
| Drug Name | Acetylcysteine |
| Target ID | BE0000760 |
| UniProt ID | Q12879 |
| Regulation Type | activator |
| PubMed IDs | 12183209; 27179791 |
| Citations | Lipton SA, Choi YB, Takahashi H, Zhang D, Li W, Godzik A, Bankston LA: Cysteine regulation of protein function--as exemplified by NMDA-receptor modulation. Trends Neurosci. 2002 Sep;25(9):474-80.@@Wright DJ, Gray LJ, Finkelstein DI, Crouch PJ, Pow D, Pang TY, Li S, Smith ZM, Francis PS, Renoir T, Hannan AJ: N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease. Hum Mol Genet. 2016 Jul 15;25(14):2923-2933. doi: 10.1093/hmg/ddw144. Epub 2016 May 14. |
| Groups | Approved; Investigational |
| Direct Classification | N-acyl-L-alpha-amino acids |
| SMILES | CC(=O)N[C@@H](CS)C(O)=O |
| Pathways | |
| PharmGKB | PA448033 |
| ChEMBL | CHEMBL600 |
