| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30059022 | HIV | ENSG00000121879.6 | protein_coding | PIK3CA | Yes | No | 5290 | P42336 Q4LE51 |
| TVIS20008729 | HPV | ENSG00000121879.6 | protein_coding | PIK3CA | Yes | No | 5290 | P42336 Q4LE51 |
| TVIS20057196 | HPV | ENSG00000121879.6 | protein_coding | PIK3CA | Yes | No | 5290 | P42336 Q4LE51 |
| TVIS20056575 | HPV | ENSG00000121879.6 | protein_coding | PIK3CA | Yes | No | 5290 | P42336 Q4LE51 |
| TVIS20019982 | HPV | ENSG00000121879.6 | protein_coding | PIK3CA | Yes | No | 5290 | P42336 Q4LE51 |
| TVIS20019983 | HPV | ENSG00000121879.6 | protein_coding | PIK3CA | Yes | No | 5290 | P42336 Q4LE51 |
| TVIS20019984 | HPV | ENSG00000121879.6 | protein_coding | PIK3CA | Yes | No | 5290 | P42336 Q4LE51 |
| TVIS44000358 | HTLV-1 | ENSG00000121879.6 | protein_coding | PIK3CA | Yes | No | 5290 | P42336 Q4LE51 |
| TVIS44005997 | HTLV-1 | ENSG00000121879.6 | protein_coding | PIK3CA | Yes | No | 5290 | P42336 Q4LE51 |
| TVIS44030971 | HTLV-1 | ENSG00000121879.6 | protein_coding | PIK3CA | Yes | No | 5290 | P42336 Q4LE51 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | PIK3CA |
|---|---|
| DrugBank ID | DB12483 |
| Drug Name | Copanlisib |
| Target ID | BE0002379 |
| UniProt ID | P42336 |
| Regulation Type | inhibitor |
| PubMed IDs | 30147333; 29127587 |
| Citations | Mensah FA, Blaize JP, Bryan LJ: Spotlight on copanlisib and its potential in the treatment of relapsed/refractory follicular lymphoma: evidence to date. Onco Targets Ther. 2018 Aug 13;11:4817-4827. doi: 10.2147/OTT.S142264. eCollection 2018.@@Markham A: Copanlisib: First Global Approval. Drugs. 2017 Dec;77(18):2057-2062. doi: 10.1007/s40265-017-0838-6. |
| Groups | Approved; Investigational |
| Direct Classification | Quinazolinamines |
| SMILES | COC1=C(OCCCN2CCOCC2)C=CC2=C1N=C(NC(=O)C1=CN=C(N)N=C1)N1CCN=C21 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3218576 |
