| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30002701 | HIV | ENSG00000126351.13 | protein_coding | THRA | No | No | 7067 | P10827 Q6FH41 |
| TVIS30086145 | HIV | ENSG00000126351.13 | protein_coding | THRA | No | No | 7067 | P10827 Q6FH41 |
| TVIS30043746 | HIV | ENSG00000126351.13 | protein_coding | THRA | No | No | 7067 | P10827 Q6FH41 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | THRA |
|---|---|
| DrugBank ID | DB04855 |
| Drug Name | Dronedarone |
| Target ID | BE0000687 |
| UniProt ID | P10827 |
| Regulation Type | inhibitor |
| PubMed IDs | 12538616 |
| Citations | Van Beeren HC, Jong WM, Kaptein E, Visser TJ, Bakker O, Wiersinga WM: Dronerarone acts as a selective inhibitor of 3,5,3'-triiodothyronine binding to thyroid hormone receptor-alpha1: in vitro and in vivo evidence. Endocrinology. 2003 Feb;144(2):552-8. doi: 10.1210/en.2002-220604. |
| Groups | Approved |
| Direct Classification | Aryl-phenylketones |
| SMILES | CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C1=C(CCCC)OC2=C1C=C(NS(C)(=O)=O)C=C2 |
| Pathways | |
| PharmGKB | PA153619853 |
| ChEMBL | CHEMBL184412 |
