| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44046321 | HTLV-1 | ENSG00000066468.24 | protein_coding | FGFR2 | Yes | No | 2263 | A0A141AXF1 D2CGD1 P21802 S4R381 |
| TVIS44046546 | HTLV-1 | ENSG00000066468.24 | protein_coding | FGFR2 | Yes | No | 2263 | A0A141AXF1 D2CGD1 P21802 S4R381 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | FGFR2 |
|---|---|
| DrugBank ID | DB09078 |
| Drug Name | Lenvatinib |
| Target ID | BE0000748 |
| UniProt ID | P21802 |
| Regulation Type | inhibitor |
| PubMed IDs | 17943726 |
| Citations | Matsui J, Yamamoto Y, Funahashi Y, Tsuruoka A, Watanabe T, Wakabayashi T, Uenaka T, Asada M: E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition. Int J Cancer. 2008 Feb 1;122(3):664-71. |
| Groups | Approved; Investigational |
| Direct Classification | Quinoline carboxamides |
| SMILES | COC1=C(C=C2C(OC3=CC=C(NC(=O)NC4CC4)C(Cl)=C3)=CC=NC2=C1)C(N)=O |
| Pathways | |
| PharmGKB | PA166153472 |
| ChEMBL | CHEMBL1289601 |
